INHIBITION OF VIRUS BY NITRIC OXIDE

摘要

A method for inhibiting the replication of a virus by exposing the virus to nitric oxide or a nitric oxide releasing, delivering or transferring substance, particularly administering a virus replication inhibitory amount of nitric oxide or a nitric oxide releasing substance to an individual having a virus infection. A method for preventing of reversing latency in a virus by exposing the latent virus to a nitric oxide synthase inhibitor, particularly a method for the treatment of a latent virus infection in an individual by administering (i) a virus latency preventing or reversing amount of a nitric oxide synthase inhibitor sufficient to render the virus replicative and then (ii) a virus replication inhibitory amount of nitric oxide or a nitric oxide-releasing substance and a composition of (i) and (ii) for such treatment, (iii) a prophylactic amount of NO(ii) to prevent latent virus from becoming replicative.