摘要 |
The present invention provides novel difluorostatone derivatives of general formula (I), which are useful as antiviral agents. More specifically, these novel compounds are useful as inhibitors of retroviral proteases required for replication, particularly the HIV-1 and HIV-2 viral proteases, in the prevention or treatment of infection by the human immunodeficiency virus (HIV), and in the treatment of consequent pathological conditions such as the acquired immunodeficiency syndrome (AIDS) in mammals capable of being infected with HIV virus.
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申请人 |
MERRELL PHARMACEUTICALS INC. |
发明人 |
FARR, ROBERT, A.;CREGGE, ROBERT, J.;JANOWICK, DAVID, A.;KOHLMAN, DANIEL, T.;VAN DORSSELAER, VIVIANE;SCHIRLIN, DANIEL, G.;TARNUS, CELINE |