发明名称 |
DIFLUOROSTATONE ANTIVIRAL AGENTS |
摘要 |
The present invention provides novel difluorostatone derivatives of general formula (I), which are useful as antiviral agents. More specifically, these novel compounds are useful as inhibitors of retroviral proteases required for replication, particularly the HIV-1 and HIV-2 viral proteases, in the prevention or treatment of infection by the human immunodeficiency virus (HIV), and in the treatment of consequent pathological conditions such as the acquired immunodeficiency syndrome (AIDS) in mammals capable of being infected with HIV virus.
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申请公布号 |
CA2195125(A1) |
申请公布日期 |
1996.02.01 |
申请号 |
CA19952195125 |
申请日期 |
1995.06.06 |
申请人 |
MERRELL PHARMACEUTICALS INC. |
发明人 |
FARR, ROBERT A.;CREGGE, ROBERT J.;JANOWICK, DAVID A.;KOHLMAN, DANIEL T.;VAN DORSSELAER, VIVIANE;SCHIRLIN, DANIEL G.;TARNUS, CELINE |
分类号 |
A61K31/415;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/445;A61K31/47;A61K31/535;A61P31/12;A61P43/00;C07C231/12;C07C237/22;C07C269/06;C07C271/22;C07D213/30;C07D213/40;C07D213/82;C07D295/15;C07D295/185;C07D295/192;C07D295/26;C07D521/00;C07F7/10;C07K5/023;C07K5/062;C07K5/065;C07K5/078;C07K5/083;(IPC1-7):C07C237/22;A61K31/16;C07C271/20;C07D211/40;C07D213/56;C07D233/61;C07D211/74;C07D213/81 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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