发明名称 DIFLUOROSTATONE ANTIVIRAL AGENTS
摘要 The present invention provides novel difluorostatone derivatives of general formula (I), which are useful as antiviral agents. More specifically, these novel compounds are useful as inhibitors of retroviral proteases required for replication, particularly the HIV-1 and HIV-2 viral proteases, in the prevention or treatment of infection by the human immunodeficiency virus (HIV), and in the treatment of consequent pathological conditions such as the acquired immunodeficiency syndrome (AIDS) in mammals capable of being infected with HIV virus.
申请公布号 CA2195125(A1) 申请公布日期 1996.02.01
申请号 CA19952195125 申请日期 1995.06.06
申请人 MERRELL PHARMACEUTICALS INC. 发明人 FARR, ROBERT A.;CREGGE, ROBERT J.;JANOWICK, DAVID A.;KOHLMAN, DANIEL T.;VAN DORSSELAER, VIVIANE;SCHIRLIN, DANIEL G.;TARNUS, CELINE
分类号 A61K31/415;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/445;A61K31/47;A61K31/535;A61P31/12;A61P43/00;C07C231/12;C07C237/22;C07C269/06;C07C271/22;C07D213/30;C07D213/40;C07D213/82;C07D295/15;C07D295/185;C07D295/192;C07D295/26;C07D521/00;C07F7/10;C07K5/023;C07K5/062;C07K5/065;C07K5/078;C07K5/083;(IPC1-7):C07C237/22;A61K31/16;C07C271/20;C07D211/40;C07D213/56;C07D233/61;C07D211/74;C07D213/81 主分类号 A61K31/415
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