发明名称 Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use.
摘要 <p>The present invention relates to novel benzimidazole derivatives characterized in that they are of the general formula I, and their therapeutically acceptable salts, <IMAGE> I in which: R1 and R2, which are identical or different, represent a hydrogen or a halogen atom, a lower alkyl radical, a hydroxyl radical, an alkoxy radical, an alkyl carboxylate radical, or an aryl or substituted aryl radical, n may take the values 0 or 1, m may take the values 2 to 4, X, Y, Z and W, which are identical or different, and which may even form part of another aromatic or nonaromatic ring, represent a nitrogen atom or a carbon atom linked to a hydrogen or to a halogen atom, or to another alkyl, aryl, carboxyalkyl, carboxylic, hydroxyl, alkyl hydroxyl, sulphonic or alkylsulphonic radical.</p>
申请公布号 GR3017643(T3) 申请公布日期 1996.01.31
申请号 GR19950402756T 申请日期 1995.10.04
申请人 LABORATORIOS DEL DR. ESTEVE, S.A. 发明人 CUBERES-ALTISENT, MARIA ROSA;FRIGOLA CONSTANSA, JORDI;PARES COROMINAS, JUAN
分类号 A61K31/55;A61K9/20;A61K31/4184;A61K31/496;A61K31/551;A61P25/20;A61P29/00;A61P37/08;A61P43/00;C07D231/12;C07D231/14;C07D235/14;C07D235/30;C07D403/12;C07D403/14;C07D521/00;(IPC1-7):C07D403/12;A61K31/41;A61K31/40;A61K31/415 主分类号 A61K31/55
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