发明名称 |
METHOD FOR GENERATING A POPULATION OF CELLS HAVING A HIGH SURFACE DENSITY OF A MHC MOLECULE-ASSOCIATED SPECIFIC EXOGENOUS PEPTIDE, AND CELL POPULATION |
摘要 |
A method for generating a population of cells having a high surface density of an MHC molecule-associated specific exogenous peptide. A population of living non-tumour mammalian cells, particularly human peripheral blood lymphocyte splenic cells, ganglion cells, cord blood cells or placental cells, wherein said cells have a surface density of one MHC molecule-associated specific exogenous peptide with the same allele restriction as MHC molecules, whic h restriction is substantially higher than that of the corresponding cells that express said native MHC molecule-associated exogenous peptide.
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申请公布号 |
WO9601891(A1) |
申请公布日期 |
1996.01.25 |
申请号 |
WO1995FR00907 |
申请日期 |
1995.07.06 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M;INSTITUT PASTEUR;LANGLADE DEMOYEN, PIERRE;KOURILSKY, PHILIPPE;ABASTADO, JEAN-PIERRE |
发明人 |
LANGLADE DEMOYEN, PIERRE;KOURILSKY, PHILIPPE;ABASTADO, JEAN-PIERRE |
分类号 |
A61K35/14;A61K39/00;C07K14/74;C12N5/02;(IPC1-7):C12N5/06;C12N5/08 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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