发明名称 New salts of 2-Ý(2,6-dichlorophenyl)amine¨phenylacetoxyacetic acid with organic basic cations
摘要 PCT No. PCT/IB95/00524 Sec. 371 Date Dec. 17, 1996 Sec. 102(e) Date Dec. 17, 1996 PCT Filed Jun. 28, 1995 PCT Pub. No. WO96/00716 PCT Pub. Date Jan. 11, 1996A salt of 2-[(2,6-dichlorophenyl)amine]phenylacetoxyacetic acid with an organic basic cation of formula (I); Wherein R1 and R2 independently are lower alkyl, or if R1 is hydrogen H-N(R1)(R2) has the meaning of arginine or lysine or if R1 is methyl H-N(R1)(R2) has the meaning of N-methylglucamine. This compound pocesses analgesic activity as well as antiinflammatory activity, suitable in the treatment of conditions such as rheumatoid arthritis, ankylosing spondylitis, lumbar pains, luxations and ocular inflammation. The compound further has an improved stability in aqueous solutions in comparison to the alkali metal salts, e.g. sodium and potassium.
申请公布号 AU2628895(A) 申请公布日期 1996.01.25
申请号 AU19950026288 申请日期 1995.06.28
申请人 CIBA-GEIGY AG 发明人 ALFRED SALLMANN
分类号 A61K31/215;A61P27/02;A61P29/00;A61P43/00;C07C215/10;C07C227/14;C07C229/26;C07C229/42;C07C279/14 主分类号 A61K31/215
代理机构 代理人
主权项
地址