发明名称 |
Methods of screening for nucleoside analogs that are incorporated by hiv reverse transcriptase and cause incorrect base pairing |
摘要 |
Methods and compositions related to HIV are disclosed. Using the methods of the present invention, nucleoside analogs may be screened for the ability to be incorporated by reverse transcriptase of human immunodeficiency virus ("HIV RT") and cause incorrect base pairing. Progressive mutation of the virus by such nucleoside analogs renders it non-viable. <IMAGE> |
申请公布号 |
AU2947595(A) |
申请公布日期 |
1996.01.25 |
申请号 |
AU19950029475 |
申请日期 |
1995.06.22 |
申请人 |
DARWIN MOLECULAR CORPORATION |
发明人 |
LAWRENCE A LOEB;JOHN M ESSIGMANN |
分类号 |
C12N15/09;A61K31/7064;C07H19/06;C12Q1/68;C12Q1/70 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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