发明名称 |
Neue N1-diverse 6-Fluor-8-difluormethoxy substituierte Chinoloncarbonsäuren |
摘要 |
<p>N1 diverse 6-fluorine-8-difluoromethoxy substituted quinolone carboxylic acids of the general formula (I) in which A is hydrogen or methyl, R<1> is phenyl, pyridyl, pyrimidyl or pyrazinyl, which may be substituted up to triply, equally or differently, by nitro, trifluoromethyl, halogen, cyano, hydroxy or by straight-chained or branched alkyl, acyl, alkoxy or alkylthio with up to 8 carbon atoms, R<2> is hydrogen or a straight-chained or branched alkyl with up to 6 carbon atoms, D or E is hydrogen and D is morpholino or E is a radical of the formula -CH2-L, in which L is morpholino or a 5-membered heteroaromatic bonded via N with up to 3 further nitrogen atoms or a group of the formula NR<3>R<4>, in which R<3> and R<4> are the same or different and are hydrogen, straight-chained or branched alkyl with up to 6 carbon atoms or an amino protective group, process for their production and their use as medicaments, especially antiviral agents.</p> |
申请公布号 |
DE4425659(A1) |
申请公布日期 |
1996.01.25 |
申请号 |
DE19944425659 |
申请日期 |
1994.07.20 |
申请人 |
BAYER AG, 51373 LEVERKUSEN, DE |
发明人 |
BENDER, WOLFGANG, DR., 42113 WUPPERTAL, DE;ROEBEN, WOLFGANG, DR., 51467 BERGISCH GLADBACH, DE;PAESENS, ARNOLD, DR., 42781 HAAN, DE;BARTEL, STEPHAN, DR., 51465 BERGISCH GLADBACH, DE |
分类号 |
C07D215/56;C07D249/08;C07D521/00;(IPC1-7):C07D401/10;C07C229/14;C12N7/06;A61K31/495;A61K31/535;A61K31/47;A61K31/505;C07D401/14;C07D295/135;C07D295/06 |
主分类号 |
C07D215/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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