| 发明名称 |
A CONJUGATE BETWEEN A MODIFIED SUPERANTIGEN AND A TARGET-SEEKING COMPOUND AND THE USE OF THE CONJUGATE |
| 摘要 |
A conjugate comprising (a) a biospecific affinity counterpart (target-seeking group) that binds to a predetermined structure and (b) a peptide that (i) contains an amino acid sequence that is derived from a superantigen, and (ii) has the ability of binding to a V beta chain of a T-cell receptor, and (iii) has a modified ability to bind to a MHC class II antigen compared to the superantigen from which the peptide is derived, which parts are covalently linked together.
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| 申请公布号 |
WO9601650(A1) |
申请公布日期 |
1996.01.25 |
| 申请号 |
WO1995SE00681 |
申请日期 |
1995.06.07 |
| 申请人 |
PHARMACIA AB;ABRAHMSEN, LARS;BJOERK, PER;DOHLSTEN, MIKAEL;KALLAND, TERJE |
发明人 |
ABRAHMSEN, LARS;BJOERK, PER;DOHLSTEN, MIKAEL;KALLAND, TERJE |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/395;A61K47/48;C07K14/31;C07K16/30;C07K16/32;C07K16/46;C07K19/00;C12N15/00;C12N15/01;C12P21/02;C12R1/44;(IPC1-7):A61K39/00 |
主分类号 |
C12N15/09 |
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