| 摘要 |
PURPOSE: To discriminate and quantify a target cell, a particle or an living organism of a biological liquid sample by connecting the antibody to an outer surface of the liposome vesicula, containing the marker substance of different specific gravity from that of the target component. CONSTITUTION: The marker liquid 16 which is visual or can be mechanically discriminated, can be diffused in the liquid carrier, and has different specific gravity from that of the target component in the sample is sealed in a thin membrane 4 of a microscopic spherical liposome vesicula 2 mainly composed of phospholipid, and one or more antibodies (A-D) 8 are connected to the outside of the membrane 4. For example, when the lymphoblast in the blood sample is detected, the marker 16 with different specific gravity from that of leukocyte is sealed in the vesicula 2, so as to layer-separate or localize the marker limphoblast from other leukocyte cell, and the specific antibody 8 to one of the lymphocyte antigen is connected to the vesicula 2. The liposome vesicula 2 reduces the density of the target T lymphocyte or locate the target T lymphocyte at the highest part of the lymphocytic layer to facilitate discrimination and quantification. |
