发明名称 Kit for pretargeting and novel pretargeting conjugates
摘要 The invention relates to a method of pretargeting therapeutic or diagnostic compounds to target cells in the body and a kit for such a method. The targeting is preferably through a specific antibody. The binding between the preinjected targeting moiety and the effector moiety is established by a zinc finger and its cognate nucleotide sequence, conjugated to the targeting or effector moiety. Also part of the invention are conjugates of zinc fingers and therapeutic or diagnostic compounds.
申请公布号 AU2887195(A) 申请公布日期 1996.01.19
申请号 AU19950028871 申请日期 1995.06.22
申请人 AKZO NOBEL N.V. 发明人 EBO SYBREN BOS;FRANCISCUS MICHAEL KASPERSEN
分类号 A61K47/48;A61K51/10 主分类号 A61K47/48
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