| 摘要 |
PURPOSE:To provide a method for drying a pyrrolidylthiocarbapenem derivative for decreasing a residual solvent, obtain crystals of a pyrrolidylthiocarbapenem derivative, excellent in solubility and stability and provide a method for producing the crystals. CONSTITUTION:This method for drying (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-2-[(3S,5 S)-5-sulfamoylaminomethyl-1-pyrrolidin-3-yl]thio-1-methyl-1-carba-2-pe nem-3- carboxylic acid comprises including a process treating the carboxylic acid using a humidified gas. |
