摘要 |
The present invention is directed to a process of making spirocycles of general structural formula: nsisting of CO-C1-3 alkyl, cyano, carboxy, carboxy C1-6 alkyl ester, carboxamide, C1-6 alkyl sulfinyl, C1-6 alkyl sulfonyl, C1-6 methanesulfonamide and halogen; R2 is selected from the group consisting of keto or alcohol, R3 is cyano, resulting in compounds which are Class III antiarrhythmic.
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