发明名称 |
BIOLOGISCH ABBAUBARE MIKROKUGELN ALS TRÄGER FÜR MAKROMOLEKÜLE |
摘要 |
A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to release the macromolecular agent at a controlled rate. The method involves emulsifying a vinyl derivative of a biodegradable hydrophilic polymer, a water-soluble monovinyl monomer and a biologically active macromolecule in water, and copolymerizing the biodegradable hydrophilic polymer and the water-soluble monovinyl monomer such that the biologically active macromolecule is entrapped therein. |
申请公布号 |
AT132035(T) |
申请公布日期 |
1996.01.15 |
申请号 |
AT19870106809T |
申请日期 |
1987.05.11 |
申请人 |
THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
DELUCA, PATRICK P.;RYPACEK, FRANTISEK |
分类号 |
A61K47/34;A61K9/16;A61K9/26;A61K9/52;A61K47/32;A61K47/36;A61K47/42;B01J13/14;C08F2/22;C08F2/44;(IPC1-7):A61K9/16 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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