PHARMACEUTICAL COMPOSITIONS CONTAINING TRICLOSAN OR DERIVATIVES THEREOF AND EDTA OR EGTA

摘要

A pharmaceutical composition in oral unit dosage form for the treatment of gastrointestinal disorders associated with Helicobacter pylori infestions wherein each unit comprises from 0.1 to 300 mg of triclosan or a derivative thereof, or an amount of an ester of triclosan or a derivative thereof, a cationic salt of an ester of triclosan or a derivative thereof, or a cationic salt of triclosan or a derivative thereof, to provide 0.1 to 300 mg of triclosan or a derivative thereof, and from 1 to 600 mg of EDTA or a salt thereof, or from 1 to 3600 mg of EGTA or a salt thereof, the weight ratio of triclosan to the EDTA or a salt thereof in each unit being in the range of from 1:2 to 1:60, or the weight ratio of triclosan to the EGTA or a salt thereof in each unit being in the range of from 1:10 to 1:500.