摘要 |
<p>The present inention relates to a process for ex vivo expansion of hematopoietic progenitor cells. This process is particularly useful in conjunction with a process for conducting autologous hematopoietic progenitor cell transplantation. In this process, hematopoietic progenitor cells are obtained from a patient prior to cytoreductive therapy. The hematopoietic progenitor cells are then expanded ex vivo with bone marrow endothelial cells or with one or more cytokines therefrom to produce a cellular preparation with an increased number of hematopoietic progenitor cells. The cellular preparation is then administered to the patient in conjunction with or after cytoreductive therapy.</p> |