DISSOLVED METHYLLITHIUM-CONTAINING COMPOSITION FOR USE IN SYNTHESIS REACTIONS

摘要

This invention relates to a dissolved methyllithium-containing composition for use in synthesis reactions (synthesis composition) and to processes of preparing the composition. In the synthesis composition the methyllithium is contained in a solvent of the general formula I <IMG> wherein R1 and R2 are independently a hydrogen, methyl or ethyl residue and R3 and R4 are a methyl or ethyl residue. To prepare the methyllithium-containing synthesis composition in accordance with the invention a) lithium powder or granular lithium is dispersed in a sol vent having the general formula I and methyl halide is added at a controlled rate, b) the reaction temperature is kept in the range form 0 to 60.degree.C, and c) the resulting lithium halide is separated from the methyl lithium solution.