Pregna-1,4-diene3,20-dione-16-17-acetal-21 esters, process for their preparation, composition, and methods for the treatment of inflammatory conditions

摘要

The present invention relates to compounds of the formula: <IMAGE> in which X1 and X2 correspond to H or F without distinction; R1 represents the following radicals: <IMAGE> <IMAGE> and R2 represents the radicals <IMAGE> in the form of an R epimer, an S epimer, or a stereoisomeric mixture of the R and S epimers in terms of the orientation of the substituents on the carbon atom at position 22, novel intermediates and a method of their preparation by hydrolysis-ketalization, and use of such compounds as drugs and/or therapeutic agents.