摘要 |
A compound of formula (I) and pharmaceutically acceptable salts and solvates thereof, wherein R<1> is a group of the formula -CR<3>R<4>(CH2)pNR<5>COR<6>; R<2> is hydrogen, halogen, C1-6alkyl, OR<7> or CO2R<7>, and may be the same or different substituent when q is 2; R<3>, R<4> and R<5>, which may be the same or different, are hydrogen or C1-6alkyl; R<6> is C1-6alkyl or C3-7cycloalkyl; R<7> is hydrogen or C1-6alkyl; n is zero, 1 or 2; p is an integer of 1, 2, 3 or 4; q is 1 or 2; and the dotted lines indicate the absence or presence of an additional bond. |