摘要 |
<p>A novel protein p72; a therapeutic method and a remedy for diabetes, each characterized by tyrosinephosphorylating the protein p72; a remedy for diabetes containing a derivative which tyrosinephosphorylates the protein p72 or a nontoxic salt thereof as the active ingredient; and a method of screening a remedy for diabetes by using the protein p72. The protein p72 tyrosinephosphorylation is an essential step for lowering the blood sugar level by glucose incorporation, and the therapeutic method and remedy for diabetes and the screening method of the invention are useful for ameliorating the hyperglycemic condition, and preventing, treating, diagnosing and/or assaying diabetes, especially noninsulin-dependent diabetes mellitus.</p> |