Proteolytic polypeptide (I) contg. the HSD triad characteristic of serine proteases and the consensus sequences (LIMV)-(ST)-A-(STAG)-HC and GDSGG in the active region, typical of the trypsin family, but unable to cleave the trypsin substrate N alpha -benzoyl-DL-Arg-p-nitroanilide or the chymotrypsin substrate N-glutaryl-L-Phe-p-nitroanilide is new. Also claimed are: (1) DNA (II) encoding (I); (2) vectors contg. (II); and (3) host cells contg. (II) or these vectors.
申请公布号
DE4422643(A1)
申请公布日期
1996.01.04
申请号
DE19944422643
申请日期
1994.06.28
申请人
MUELLER, WERNER E. G., PROF. DR., 65203 WIESBADEN, DE
发明人
MUELLER, WERNER E. G., PROF. DR., 65203 WIESBADEN, DE;RINKEVICH, BARUCH, DR., 65203 WIESBADEN, DE