发明名称 Antihypertensive 3-piperidinyl-indazole derivatives.
摘要 <p>Novel antihypertensive 3-piperidinyl-indazole derivatives of formula <CHEM> wherein R<1> is hydrogen or C1-6alkyl; R<2> is hydrogen; C1-6alkyl; substituted C1-6alkyl; optionally substituted phenyl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl or phenylcarbonyl, wherein phenyl may be substituted; R<3> and R<4> are hydrogen, halo, hydroxy, C1-6alkyloxy or C1-6alkyl; Q is a bicyclic heterocyclic radical of formula <CHEM> the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are antihypertensive agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.</p>
申请公布号 GR3017435(T3) 申请公布日期 1995.12.31
申请号 GR19950402560T 申请日期 1995.09.18
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 VANDENBERK, JAN;KENNIS, LUDO EDMOND JOSEPHINE;VAN HEERTUM, ALBERTUS H.M.T.
分类号 A61K31/4184;A61K31/44;A61K31/4427;A61K31/445;A61K31/505;A61P1/12;A61P3/04;A61P9/12;A61P25/00;A61P25/06;A61P25/18;A61P25/24;A61P25/30;A61P25/32;A61P25/34;A61P43/00;C07D401/14;C07D471/04;C07D498/04;C07D513/04;C07D521/00;(IPC1-7):C07D471/04;A61K31/42;A61K31/425;A61K31/495 主分类号 A61K31/4184
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