发明名称 |
USE OF .BETA.GALNAC(1-4).BETA.GAL CONJUGATES TO TREAT CANDIDA INFECTION |
摘要 |
A method of treating Candida albicans infection is disclosed. In one embodiment, for treatment of oral or vaginal infection, the treatment is by topical application of a composition of conjugates that are each composed of a carrier structure and multiple .beta.GalNac(1-4).beta.Gal moieties attached to the structure. In another embodiment, for treatment of systemic infection, the treatment is by parenteral administration of a humanized form of a mouse monoclonal antibody produced by mouse hybridoma cell line Fm16 or cell line PK99H.
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申请公布号 |
CA2192827(A1) |
申请公布日期 |
1995.12.28 |
申请号 |
CA19952192827 |
申请日期 |
1995.06.16 |
申请人 |
PENCE |
发明人 |
IRVIN, RANDALL T.;LEE, KOK KHEONG;HODGES, ROBERT S.;SHETH, HASMUKH B.;YU, LEI |
分类号 |
C12N15/02;A61K31/70;A61K31/7024;A61K31/7028;A61K38/00;A61K39/395;A61K47/48;A61P31/04;C07H13/06;C07H15/04;C07K16/12;C07K16/14;C12P21/08;C12R1/91;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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