| 发明名称 |
Modified VP1/P2A regions of the rhinoviral system |
| 摘要 |
The invention relates to systems which enable mutations to be inserted in the VP1/2A region and in the total coding region of protease 2A, test systems for investigating the ''cis'' and ''trans'' activity, oligonucleotides which code the mutations, as well as the oligopeptides derived therefrom and their use. It also relates to oligopeptides which can be split off protease 2A in trans with varying efficiency, and their use. |
| 申请公布号 |
IE66395(B1) |
申请公布日期 |
1995.12.27 |
| 申请号 |
IE19900002270 |
申请日期 |
1990.06.22 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH. |
发明人 |
SOMMERGRUBER WOLFGANG DR;MAURER-FOGY INGRID DR;VOLKMANN PETER DR;FESSL FRIEDERIKE DIPL ING;KUECHLER ERNST DR;BLAAS DIETER DIPL ING DR;ZORN MANFRED MAG;AUER HERBERT ING;SKERN TIMOTHY DR |
| 分类号 |
C12N15/09;A61K31/70;A61K38/00;A61K38/55;A61K39/00;A61K39/395;A61P31/12;C07K7/00;C07K7/06;C07K7/08;C07K14/00;C07K14/095;C07K14/81;C07K16/08;C07K16/10;C07K16/40;C12N;C12N9/50;C12N15/41;C12N15/47;C12N15/57;C12N15/62;C12Q1/70;(IPC1-7):C12N15/41;C12N15/70;C12P21/02 |
主分类号 |
C12N15/09 |
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