发明名称 Solution of sparfloxacin, its preparation and salt of which it is composed
摘要 PCT No. PCT/FR92/00891 Sec. 371 Date Mar. 25, 1994 Sec. 102(e) Date Mar. 25, 1994 PCT Filed Sep. 25, 1992 PCT Pub. No. WO93/05782 PCT Pub. Date Apr. 1, 1993.This invention relates to a pharmaceutical composition comprising sparfloxacin and a stable aqueous solution of sparfloxacin of the formula (I): <IMAGE> (I) comprising sparfloxacin, one or more polyhydroxymonocarboxylic acids, or lactone derivatives thereof, at least in a stoichiometric quantity with respect to sparfloxacin, and, optionally, an excess of said polyhydroxymonocarboxylic acid or another pharmaceutically acceptable acid for ensuring full solubilization of the salt so formed, not exceeding 5, and optionally an isotonic agent and/or other pharmaceutically acceptable additives.
申请公布号 US5478829(A) 申请公布日期 1995.12.26
申请号 US19940211057 申请日期 1994.03.25
申请人 RHONE-DPC EUROPE 发明人 CONRATH, GUILLAUME
分类号 A61K9/08;A61K9/00;A61K31/47;A61K31/495;A61K47/12;A61K47/26;(IPC1-7):A61K31/495;C07D401/04 主分类号 A61K9/08
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