发明名称 |
Three-dimensional stromal cell and tissue culture system |
摘要 |
The present invention relates to an improved three-dimensional cell culture system in which cells are grown on a three-dimensional matrix while cycling the cultures between metabolically favorable and metabolically unfavorable (but noncytotoxic) conditions. The invention is based, at least in part, on the discovery that cycling the cultures in this manner optimizes the formation of extracellular matrix and produces an overall structure that more closely resembles naturally occurring tissue.
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申请公布号 |
US5478739(A) |
申请公布日期 |
1995.12.26 |
申请号 |
US19920965476 |
申请日期 |
1992.10.23 |
申请人 |
ADVANCED TISSUE SCIENCES, INC. |
发明人 |
SLIVKA, SANDRA R.;LANDEEN, LEE |
分类号 |
C12N5/071;(IPC1-7):C12N5/00;A61F2/10 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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