| 摘要 |
Prostacyclin (PGI2) analogues represented by the general formula I <CHEM> wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, lower alkenyl, lower alkynyl, lower aralkynyl, lower alkyloxy, arythio, or cyano; R3 and R4 each is hydrogen or a hydroxy-protecting group; R5 is straight or branched alkyl which may be substituted with a heterocycle, straight or branched alkynyl, or cycloalkyl; the wavy line indicates R- or S-configuration, or their mixture; or a salt thereof being used as antithrombotic and antiulcer drugs. |
