发明名称 SCREEN FOR INHIBITORS OF CHITINASE
摘要 <p>The present invention is directed to a method for screening samples for the identification of agents exhibiting potential fungicidal and insecticidal activity for a wide variety of agricultural, medical and pharmaceutical uses. The method utilizes cells that comprise a plasmid-born CTS gene of Saccharomyces cerevisiae, which allows for over expression of chitinase. Compounds that inhibit a hydrolytic action on methyl- umbelliferyltriacetyl chitotriose, but which are not toxic to the cells are detected by decrease in conversion of substrate.</p>
申请公布号 WO1995034678(A1) 申请公布日期 1995.12.21
申请号 US1995007207 申请日期 1995.06.07
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