Pharmaceutical composition

摘要

A method of making a pharmaceutical composition comprising an inclusion complex of a beta -cyclodextrin or a derivative thereof and a sparingly water-soluble non-steroidal anti-inflammatory drug such as diclofenac sodium, the composition being in solid form which is adapted to be dissolved in water to provide a clear or slightly opaque solution for oral administration, includes the steps of forming a paste from the beta -cyclodextrin or the derivative thereof and the NSAID with a wetting solution, mixing the paste with addition of further wetting solution if necessary, and drying the product to produce the inclusion complex which dissolves in water to provide a clear or slightly opaque solution.