Mfr. of carbamazepine (I) comprises (a) reacting a suspension of iminostilbene (II) in a cyclic ether with phosgene at 20-70 deg C. and (b) neutralising and amidating the resulting iminostilbene carbonyl chloride (III) with ammonia at 50-100 deg C. under 1-7 bar pressure.
申请公布号
DE4421294(A1)
申请公布日期
1995.12.21
申请号
DE19944421294
申请日期
1994.06.17
申请人
CHEMIE LINZ (DEUTSCHLAND) GMBH, 65185 WIESBADEN, DE
