发明名称 COMPOSITIONS AND METHODS FOR THE TREATMENT OF TUMORS
摘要 The invention concerns a method for inhibiting the growth and/or causing regression of tumors by administering a therapeutically effective dose of a procoagulant and a cytokine, preferably TNF-.beta., TNF-.alpha. and/or IL-1. In a specific aspect, the invention concerns a method for tumor treatment by the administration of a therapeutically effective amount of a thrombomodulin inhibitor and a cytokine. The invention also concerns thrombomodulin inhibitors and pharmaceutical compositions used in the course of these treatments.
申请公布号 CA2191065(A1) 申请公布日期 1995.12.21
申请号 CA19952191065 申请日期 1995.06.08
申请人 GENENTECH, INC. 发明人 VEHAR, GORDON A.
分类号 C12N15/02;A61K38/00;A61K38/06;A61K38/21;A61K38/22;A61K38/43;A61K38/46;A61K38/48;A61K38/55;A61K39/395;A61K45/00;A61P35/02;C07K16/18;C07K16/40;C12N5/10;C12P21/08;(IPC1-7):A61K38/36;A61K38/19 主分类号 C12N15/02
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