发明名称 Antimicrobial oil-in-water emulsions
摘要 An antibacterial oil-in-water emulsion for inhibiting the growth of Helicobacter pylori is disclosed. The oil-in-water emulsion of the invention comprises droplets of an oily discontinuous phase dispersed in a continuous phase. The oily discontinuous phase contains an oil carrier and a glycerol ester selected from the group consisting of glycerol monooleate and glycerol monostearate. The emulsion can be positively charged, negatively charged or chargeless. In one embodiment, the emulsion is positively charged and further comprises a cationic halogen-containing compound having a C12-C16 chain as a positive charge producing agent. In another embodiment, the emulsion is negatively charged and further comprises an negative charge producing agent having a C12-C22 chain. The disclosed emulsions can be administered to individuals, for example, orally, to treat or prevent Helicobacter pylori infections.
申请公布号 AU2593795(A) 申请公布日期 1995.12.18
申请号 AU19950025937 申请日期 1995.05.18
申请人 NOVAVAX, INC. 发明人 D. CRAIG WRIGHT
分类号 A61K9/107;A01N25/04;A01N33/12;A61K9/127;A61K31/14;A61K31/23;A61K31/231;A61K31/57;A61K31/575;A61K45/06;A61K47/44;A61P17/00;A61P31/00;A61P31/04;A61P31/12 主分类号 A61K9/107
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