发明名称 Complex van een analoog van menselijk insuline, alsmede een dergelijk complex omvattende formulering.
摘要 The present invention discloses a human insulin analog hexamer complex and formulations. More specifically, the present invention relates to various parenteral formulations, which comprise: human insulin analogs in a hexamer conformation, zinc ions, and at least three molecules of a phenolic derivative selected from the group consisting of m-cresol, phenol, or a mixture of m-cresol and phenol. The formulation provides a rapid onset of action.
申请公布号 NL1000566(A1) 申请公布日期 1995.12.18
申请号 NL19951000566 申请日期 1995.06.14
申请人 ELI LILLY AND COMPANY 发明人 DIANE LEE BAKAYSA;DAVID NETTLESHIP BREMS;BRUCE HILL FRANK;HENRY ACKEN HAVEL;ALLEN HOWARD PEKAR
分类号 C07K14/62;A61K31/05;A61K33/30;A61K38/28;A61K45/06;A61K47/02;A61K47/10;A61P3/08;A61P3/10;A61P5/00;A61P5/48;A61P9/00;A61P13/12;A61P25/00;A61P27/02 主分类号 C07K14/62
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