Compositions of transactivating proteins of human immunodeficiency virus

摘要

The inventions provides compositions and a novel method of immunization directed against released transactivating proteins of certain target viruses that are taken up by other cells, including particularly HIV and other integrating and chronically infecting viruses. The method employs TAT immunogens, which are capable of eliciting high titer antibody to the native TAT protein, especially the regions involved in cellular uptake.