| 摘要 |
The invention relates to magnetic resonance imaging. In particular, the invention relates to compounds of general structure (I), wherein R1 is selected from the group consisting of hydrogen, C1-C8 alkyl, hydroxy, C1-C8 alkoxy, C1-C8 hydroxyalkyl, C1-C8 acyl, C6-C10 aryl, and C6-C10 aryloxy; R2, R3 and R4 may be the same or different and are selected from the group consisting of hydrogen, C1-C8 alkyl, C1-C8 hydroxyalkyl, C1-C8 alkoxyalkyl, -CH2CO2Y and CH2CONR5R6 where R5 and R6 may be the same or different and are selected from the group consisting of hydrogen, C1-C8 alkyl, C1-C8 hydroxyalkyl and C1-C8 alkoxyalkyl; R5 and R6 may form a 5- or 6-membered carbocyclic ring optionally containing singularly or in combination nitrogen, oxygen or sulfur; m, n and p may be the same or different and are selected from an integer from 0 to about 6; X is selected from the group consisting of -CH2-, -O-, -S-, -SO2-, -CH2CH2-, -CH2O-, -CH2S-, -CH2SO2-, CH2NR7 and -N-R7-, where R7 is selected from the group consisting of hydrogen, hydroxy, C1-C8 alkyl, C1-C8 hydroxyalkyl and C1-C8 alkoxyalkyl and compositions comprising the compound. |
