摘要 |
<p>Preparations of radiolabelled bone scanning agents are improved by adding energy to the reconstituted kit in the form of heat. The preparations may be heated by autoclaving, boiling, microwaving, or sonicating. The improved agent exhibits more rapid soft tissue clearance which allows scanning of patients to be accomplished at shorter times after injection of the agent and reduces the radiation exposure to non-target tissues. These energy-modified formulations are also more stable than conventional formulations prepared at room temperature.</p> |