发明名称 NOVEL TAXOIDS, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF
摘要 <p>This invention relates to taxoids of general formula (I), their preparation and the pharmaceutical compositions which contain them. The products of general formula (I) have notable antitumoral properties. In the general formula (I), Ar represents an aryl radical, R represents a hydrogen atom or an acetyl or alkoxyacetyl radical, R1 represents a benzoyl radical or a radical R2-O-CO- in which R2 represents an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical, and R3 represents an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted aryl (with the exception of unsubstituted phenyl) or heterocyclyl radical. <IMAGE> (I)</p>
申请公布号 CZ9502237(A3) 申请公布日期 1995.12.13
申请号 CZ19950002237 申请日期 1994.02.28
申请人 RHONE-POULENC RORER S.A. 发明人 BOUCHARD HERVE;BOURZAT JEAN DOMINIQUE;COMMERCON ALAIN;PULICANI JEAN PIERRE
分类号 A61K31/335;A61K31/337;A61P35/00;C07D305/14;(IPC1-7):C07D305/14 主分类号 A61K31/335
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