发明名称 |
PROCESS FOR PRODUCING HIGH-PURITY EICOSAPENTAENOIC ACID OR ESTER THEREOF. |
摘要 |
Eicosapentaenoic acid or an ester thereof, having a purity as high as at least 99 % and being useful for preventing or treating thrombosis, can be obtained in a recovery of 55 % or above by subjecting a mixture of fatty acids or esters thereof obtained from a natural fat or oil containing eicosapentaenoic acid or derivatives thereof to precise fractional distillation in a high vacuum by using a number of, particularly at least three, distillation columns to obtain a fraction mainly comprising C20 fatty acids or esters thereof, and subjecting this fraction to reversed phase column chromatography for fractional purification. <IMAGE> |
申请公布号 |
EP0610506(A4) |
申请公布日期 |
1995.12.13 |
申请号 |
EP19920922597 |
申请日期 |
1992.10.28 |
申请人 |
NIPPON SUISAN KABUSHIKI KAISHA |
发明人 |
FURIHATA, KIYOMI, CHUO-INSTITUTE OF;HATA, KAZUHIKO, CHUO-INSTITUTE OF |
分类号 |
C07C69/587;C07C51/44;C07C57/03;C07C67/54;C07C67/56;C11B3/10;C11B3/12;C11C1/08;C11C1/10 |
主分类号 |
C07C69/587 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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