发明名称 |
Cell binding agent conjugates of analogues and derivatives of CC-1065 |
摘要 |
Novel cytotoxic agents comprising a cell binding agent chemically linked to one or more analogue or derivative of CC-1065 are described. The therapeutic use of the cytotoxic agents is also described. These cytotoxic agents have therapeutic use because they deliver the cytotoxic drugs to a specific cell population in a targeted fashion.
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申请公布号 |
US5475092(A) |
申请公布日期 |
1995.12.12 |
申请号 |
US19940210742 |
申请日期 |
1994.03.21 |
申请人 |
IMMUNOGEN INC. |
发明人 |
CHARI, RAVI V. J.;GOLDMAKHER, VIKTOR S.;BLATTLER, WALTER A. |
分类号 |
A61K38/22;A61K39/395;A61K47/48;A61P31/00;A61P33/00;A61P35/00;A61P37/00;C07D405/12;C07D487/04;C07D491/048;C07D519/00;(IPC1-7):C07K16/00;C07K17/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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