| 摘要 |
PCT No. PCT/JP95/00260 Sec. 371 Date Jun. 13, 1995 Sec. 102(e) Date Jun. 13, 1995 PCT Filed Feb. 23, 1995 PCT Pub. No. WO95/22973 PCT Pub. Date Mar. 8, 1995An injectable oil-in-water emulsion composition comprises an antifungal triazole compound of the following formula (I) <IMAGE> (I) wherein Ar represents a substituted phenyl group; R1 and R2 represent, independently, a hydrogen atom or a lower alkyl group, or R1 and R2 may together form a lower alkylene group; R4 represents a hydrogen atom or an acyl group; and A represents an optionally substituted cyclic amide group bonded through a nitrogen atom, or a salt thereof. The solubility of the triazole compound having poor water-solubility and fat-solubility can remarkably be increased by dispersing in water with use of an oil component (e.g. a triglyceride of fatty acids) and an emulsifier (e.g. a phospholipid). |
