BILE SALTS STIMULATED LIPASE VARIANTS, DNA MOLECULES ENCODING THEM AND TRANSGENOUS MAMMALS, EXCEPT OF HUMAN BEINGS

摘要

The invention discloses nucleic acids encoding variant Bile Salt Stimulated Lipase (BSSL; EC 3.1.1.1). The encoded variant BSSL enzymes maintain catalytic activity but contain fewer glycosylation sites that full-length BSSL. This reduced glycosylation facilitates purification and characterization of recombinant BSSL proteins.