摘要 |
<p>A compound of formula (I), wherein A is C1-6alkyl, -O-C1-6alkyl, -O-phenyl or phenyl, optionally substituted by C1-3alkyl or halogen; n is an integer of from 0 to 3; W is a group of formula (i), (ii) or (iii) wherein R is hydrogen or C1-4alkyl, x is -O-, -S-, -NH-, or -CH2-, Y is oxygen or sulphur and the chiral centre * in formula (i) or (ii) is in its (S) or (R) form or is a mixture thereof in any proportions; and Z is a group of formula (iv) -CH2CH2NR1R2, (v) or (vi) wherein R?1 and R2¿ are independently selected from hydrogen and C¿1-4?alkyl and R?3¿ is hydrogen or C¿1-4?alkyl; and salts, solvates and physiologically functional derivatives thereof.</p> |