| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS |
| 摘要 |
The present invention describes compounds, methods and compositions effective to treat mast-cell mediated inflammatory conditions, such as conjunctivitis, asthma and allergic rhinitis. The compounds of the invention comprise novel mono- and di-aminomethylbenzyl, aminobenzyl, guanidylbenzyl and benzyl tryptase inhibitors. The compositions for treating mast-cell mediated inflammatory conditions include oral, inhalant and topical preparations as well as devices comprising such preparations.
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| 申请公布号 |
WO9532945(A1) |
申请公布日期 |
1995.12.07 |
| 申请号 |
WO1995US06926 |
申请日期 |
1995.05.31 |
| 申请人 |
ARRIS PHARMACEUTICAL CORPORATION |
发明人 |
LUM, ROBERT, T.;GSCHWEND, HEINZ, W.;BAUER, BARR, E.;KUO, ELAINE;RICE, KEN |
| 分类号 |
C07D317/32;A61K9/12;A61K31/165;A61K31/27;A61K31/335;A61K31/357;A61K31/40;A61K31/57;A61K45/00;A61K45/06;A61P11/00;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P37/08;A61P43/00;C07C233/36;C07C233/40;C07C233/78;C07C235/10;C07C237/22;C07C237/34;C07C237/36;C07C271/20;C07C271/22;C07C275/24;C07C275/26;C07C279/18;C07D207/16;(IPC1-7):C07C279/18;C07C233/51;A61K31/16;A61K31/155;A61K31/17 |
主分类号 |
C07D317/32 |
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