发明名称 |
METHOD FOR PURIFYING SOMATOTROPIN MONOMERS |
摘要 |
There is provided a method for purifying a refold somatotropin monomer from a mixture of somatotropin monomers and somatotropin oligomers in an aqueous solution having a urea concentration of greater than 3 molar by the addition of an acid to reduce the pH of the solution to below about 7.7 to selectively precipitate the oligomers in the most part.
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申请公布号 |
WO9532222(A1) |
申请公布日期 |
1995.11.30 |
申请号 |
WO1995US06187 |
申请日期 |
1995.05.15 |
申请人 |
MONSANTO COMPANY |
发明人 |
KULVARANON, SUVIT;OWSLEY, DENNIS, CLARK |
分类号 |
C07K14/61;(IPC1-7):C07K14/61 |
主分类号 |
C07K14/61 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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