METHOD OF MANUFACTURE OF (-)GALANTHAMINE IN HIGH YIELD AND PURITY SUBSTANTIALLY FREE OF EPIGALANTHAMINE
摘要
(-)-Galanthamine is obtained in substantially high yield and purity substantially without concomitant production of epigalanthamine by conversion of racemic narwedine to (-)-narwedine and subsequent reduction to (-)-galanthamine using bulky organo-aluminum or organo-boron reducing agents.
申请公布号
WO9527715(A3)
申请公布日期
1995.11.30
申请号
WO1995US04888
申请日期
1995.04.07
申请人
CIBA-GEIGY CORPORATION;SHIEH, WEN-CHUNG;CARLSON, JOHN, ALAN
