| 摘要 |
PCT No. PCT/IB95/00288 Sec. 371 Date Oct. 28, 1996 Sec. 102(e) Date Oct. 28, 1996 PCT Filed Apr. 24, 1995 PCT Pub. No. WO95/30421 PCT Pub. Date Nov. 16, 1995The invention relates to the use of certain methanebisphosphonic acid derivatives (for the manufacture of a pharmaceutical composition) for the prevention and treatment of prosthesis loosening and prosthesis migration in mammals including man. |
