| 摘要 |
A class of 1,5-diphenyl pyrazoles is described for the treatment of inflammation, including treatment of pain and disorders such as arthritis. Compounds of particular interest are of Formula I <IMAGE> (I) wherein R1 is methylsulfonyl; wherein R2 is selected from -CF3, -CF2Cl, -CF2H, -CF2CF3 and -CF2CF2CF3; and wherein R3 is fluoro or chloro; or a pharmaceutically-acceptable salt thereof. |
