| 发明名称 |
Single chain proteins with FHS suppressing activity isolated from follicular fluid and uses thereof |
| 摘要 |
Polypeptides exhibiting an inhibitory action over follitropin are disclosed. These polypeptides are designated follitropin suppressing proteins, or "FSP's," and range in size from 30 to 60 kD as determined by SDS-PAGE. Uses for FSP's, including regulation of fertility and as immunogens, are disclosed.
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| 申请公布号 |
US5470826(A) |
申请公布日期 |
1995.11.28 |
| 申请号 |
US19930145194 |
申请日期 |
1993.11.03 |
| 申请人 |
BIOTECHNOLOGY AUSTRALIA PTY LTD.;MONASH UNIVERSITY;MONASH MEDICAL CENTRE;ST. VINCENTS INSTITUTE OF MEDICAL RESEARCH |
发明人 |
DE KRETSER, DAVID M.;BURGER, HENRY G.;HEARN, MILTON T. W.;MILNE-ROBERTSON, DAVID M.;WETTENHALL, RICHARD E. H.;MCLACHLAN, ROBERT I.;DE VOS, FIONA |
| 分类号 |
A61K38/00;A61K38/04;A61K39/395;A61P5/00;A61P13/02;A61P15/00;C07K1/20;C07K14/00;C07K14/47;C07K14/575;C07K16/00;C07K16/18;C07K16/26;C12P21/08;(IPC1-7):A61K38/22 |
主分类号 |
A61K38/00 |
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