发明名称 RECOMBINANT DNA PRODUCT AND METHOD
摘要 The present invention provides an altered antibody molecule (AAM) having a hinge region which has a different number of cysteine residues from that found in the hinge region normally associated with the CH1 domain of the antibody molecule and a process for producing the same using recombinant DNA technology.
申请公布号 CA1337640(C) 申请公布日期 1995.11.28
申请号 CA19880576562 申请日期 1988.09.06
申请人 CELLTECH LIMITED 发明人 BODMER, MARK WILLIAM;ADAIR, JOHN ROBERT;WHITTLE, NIGEL RICHARD
分类号 G01N33/531;A61K39/395;C07K1/22;C07K14/00;C07K16/00;C07K16/18;C07K16/30;C07K19/00;C12N5/10;C12N15/00;C12N15/09;C12N15/13;C12N15/20;C12P21/00;C12P21/02;C12P21/08;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12N15/13 主分类号 G01N33/531
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