| 发明名称 |
Method for producing TH-independent cytotoxic T lymphocytes |
| 摘要 |
The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.
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| 申请公布号 |
US5470730(A) |
申请公布日期 |
1995.11.28 |
| 申请号 |
US19940287111 |
申请日期 |
1994.08.08 |
| 申请人 |
IMMUNEX;FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
GREENBERG, PHILLIP D.;OVERELL, ROBERT W. |
| 分类号 |
A61K35/14;C07K14/715;C12N5/0783;(IPC1-7):C12N15/12;C12N5/10 |
主分类号 |
A61K35/14 |
| 代理机构 |
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| 主权项 |
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